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MELBOURNE, June 21 (Xinhua) -- A study published on Wednesday has brought Australian researchers a step closer to understanding gene mutations that can cause breast cancer.
Scientists from the University of Melbourne and Peter MacCallum Cancer Centre have for the first time accurately established the likelihood that carriers of the BRCA1 and BRCA2 gene mutations will contract cancer.
The BRCA mutations are hereditary issues whereby chromosomes within the BRCA1 or BRCA2 genes, both of which are tumour-suppressing genes Adidas Dame 4 Sneakers Black Red Men's Sale , are misplaced, drastically increasing the likelihood of developing breast or ovarian cancer.
The study found that women with the BRCA1 mutation had, on average, a 72 percent chance of developing breast cancer by the time they were 80 years old and a 44 percent likelihood of contracting ovarian cancer.
For women with the BRCA2 Adidas Questar Flyknit Boost Pink White Women's Cheap , the chances were slimmer at 69 and 17 percent respectively for breast and ovarian cancer.
Almost 10,000 women from around the world with the mutations were assessed over 20 years for the landmark study.
John Hopper, lead researcher from the University of Melbourne, said that the fact that researchers were able to analyze the participants and their risk factors over the course of 20 years rather than assess retrospective data made the study the most reliable one done yet.
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"An important finding was that carrier's risk was virtually the same from age 50 years on, meaning that carriers should continue to be vigilant with screening," Hopper said.
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